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  • www.misonou.org
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Our research focuses on the Neurobiology of protein regulation, particularly ion channels and Alzheimer's tau protein. Ion channels are the engine that generates electrical signals for neurons to transmit signals and to compute. We aim to understand..

Relevance: 46.702717
  • www.dacosta.net
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Evolved to convert chemical signals into electrical impulses, ligand-gated ion channels are Nature's ultimate molecular sensors, controlling fundamental physiological processes. The dacosta]:[lab seeks an atomic-level understanding of ligand-gated..

Relevance: 30.973194
  • moronilab.com
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Ion channels are membrane proteins that control cell electrical signals in response to a variety of physical and chemical stimuli. We study how stimuli are perceived and transduced at the molecular level in order to understand common gating..

Relevance: 29.111485
  • www.channel-proteomes.com
The Institute of Physiology II at the University of Freiburg (Germany) with its long-standing interest in protein-encoded specificity of signal transduction and Logopharm GmbH, a biotechnology company dedicated to development of advanced proteomic..

Relevance: 26.60873
  • www.channel-proteomes.com
The Institute of Physiology II at the University of Freiburg (Germany) with its long-standing interest in protein-encoded specificity of signal transduction and Logopharm GmbH, a biotechnology company dedicated to development of advanced proteomic..

Relevance: 26.60873
  • schlessingerlab.org
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Developing and applying computational tools to annotate protein function and advance drug discovery... We study the structure and function of Solute Carrier (SLC) transporters and develop novel strategies to characterize their function... We..

Relevance: 26.08545
  • theplesslab.com
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Another key area of interest is the sodium leak channel NALCN. This ion channel is required for survival in mammals and gain- or loss-of-function mutations can result in devastating diseases in humans. We have recently shown that NALCN is only..

Relevance: 24.878605
  • pharm.ucsf.edu
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The neurotransmitter glutamate drives specific changes in the functioning of synaptic glutamate-gated ion channels. These changes modulate the strength of synaptic transmission, encode information, and allow for adaptive behaviors. We are developing..

Relevance: 23.24401
  • www.logopharm.com
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LOGOPHARM GmbH is a research-oriented biotech company that provides advanced solutions in proteomic target and biomarker R&D. The company located at Freiburg (Germany) was founded 2005 by a team of leading scientists and business experts. It combines..

Relevance: 23.128424
  • baistructurelab.org
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Proteins are involved in virtually every process within biological systems, and the function that a protein assumes depends on its structure. Determining the structure of a protein is of fundamental importance to understanding protein interactions,..

Relevance: 23.118725
  • www.ionera.de
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Ionera provides a universal chip platform for ion-conductance based analytics. We develop and customize multielectrode cavity array (MECA) chips, nanopore and channel protein reconstitution kits and assays... Ionera's mission is to provide a..

Relevance: 23.116537
  • www.seedsupply.co.jp
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We are constructing binder collections using our protein library and compound library. We have already had binders of some SLC transporters and GPCRs as pipelines in discovery stage... By utilizing a single, streamlined method across all target..

Relevance: 22.780306
  • juliuslab.ucsf.edu
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Nociception is the process whereby specialized somatosensory nerve fibers (nociceptors) detect noxious stimuli and transmit this information to the spinal cord and brain, ultimately evoking a percept of discomfort or pain. Nociceptors are faced with..

Relevance: 22.59599
  • www.drmichaelbutterworth.com
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Research in the Butterworth lab is focused on the regulation of ion channels in epithelial cells of the body. We have particular expertise investigating the epithelial sodium channel (ENaC) and its regulation in the kidney and human airway. Defects..

Relevance: 22.50598
  • www.drugtargetontology.org
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Drug Target Ontology (DTO) is being developed at the University of Miami in the research group of Stephan Schürer. DTO was developed as part of the Illuminating the Druggable Genome (IDG) project (https://commonfund.nih.gov/idg/overview), is..

Relevance: 22.264984
  • leadxpro.com
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leadXpro is the partner of choice for membrane protein structural biology and can boost any drug discovery project from gene to lead... Using its unique technology platform, leadXpro is developing proprietary preclinical compounds with high efficacy..

Relevance: 22.17935
  • www.brukinsa.com
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Bruton's tyrosine kinase (BTK) is a protein that signals to cancerous B cells, helping them to grow and spread..

Relevance: 22.092424
  • bionymer.com
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Our vision is to change the way we understand biology by directly measuring the common currency of all biological processes - ion transport. We have teamed up with biologists and medical practitioners to create tools capable of converting biological..

Relevance: 21.561789
  • ionchannelpharmacology.com
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Ion Channel Pharmacology (ICP) is a research and development enterprise involved in studying drugs that bring about their effects by modulating ion channel functions. Most drugs, one way or another, modulate ion channels either by activating or..

Relevance: 21.119282
  • www.sgp2021.com
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The 74th Annual Meeting of the Society of General Physiologist will be the first international conference fully dedicated to the topic of Ion Channels and Transporters (ICTs) in the immune system. This meeting will provide a unique opportunity for..

Relevance: 21.035904
  • www.caver.cz
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CAVER is a software tool for analysis and visualization of tunnels and channels in protein structures. Tunnels are void pathways leading from a cavity buried in a protein core to the surrounding solvent. Unlike tunnels, channels lead through the..

Relevance: 20.776505
  • www.thecooperlab.org
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We are affiliated with the Neurology Department, Neuroscience Department, Molecular and Human Genetics, Intellectual and Developmental Disabilities Research Center, and the Brain Disorders and Development Training Program of Baylor College of..

Relevance: 20.763723
  • www.intracellularchannels.com
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Our research focus is to establish the molecular identity of mitochondrial ion channels, elucidate their targeting mechanism and study their biophysical properties. At functional level we focus on how mitochondrial ion channels regulate cellular..

Relevance: 20.66595
  • darkmatter.ucsf.edu
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UCSF is one of three hubs of the IDG. Our objective is to apply transformative scalable technology platforms and streamlined experimental workflows incorporated with multiple robust assay and physiological perturbation protocols for large-scale..

Relevance: 20.499472
  • www.p53reactivation.com
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Aprea Therapeutics is a biopharmaceutical company focused on developing novel cancer therapeutic candidates with the potential to reactivate mutant p53 protein... p53 is a tumor suppressor protein that regulates a complex network of signals that can..

Relevance: 20.48378
  • www.biophystech.org
We wish to understand complex chemical and physical phenomena in biological systems at previously unattainable levels of detail. In particular, we study how shape-, size- and dimension-dynamics can be used to control chemistry in small-scale..

Relevance: 20.085815
  • telegramfxbacktest.io
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TelegramFxBacktest has the same settings of strategies. So, When if you find an accurate telegram channels with our telegram backtesting software, you will be able to copy signals from that channels automatically with the same settings...

Relevance: 20.078047
  • www.cryobiophysica.com
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CryoBioPhysica is a privately owned biotech research company based in Maryland and originally engaged in basic protein and low temperature stress research. The company has developed novel and powerful methods for anion, cation and combined ion..

Relevance: 19.664352
  • www.armgo.com
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ARMGO is a venture-backed biotech company developing Rycals®, novel small molecule drugs that target the ryanodine receptor calcium ion channels (RyR)...

Relevance: 19.6286
  • chanpharm.com
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ChanPharm is a contract research organisation (CRO) offering compound screening and selectivity profiling for a broad range of ion channels. ChanPharm's scientists have made significant contributions to the field of ion channel research over more..

Relevance: 19.421682