TRANSLATIONAL GENOMICS

The Department of Translational Genomics was founded on December 1 st, 2011 and is chaired by the Director Prof. Roman Thomas. In the last few years, the Department has grown steadily and now comprises 9 different working groups that work closely and interdisciplinary on common research questions... We build our Department on a portfolio of established technological platforms, covering approaches involving genomics, immunomics, cellular models, genetically engineered mouse models (GEMMs) and imaging, as well as computational efforts to understand the molecular evolution of cancer. Particular emphasis is placed on carefully interrogating the discoveries made in large scale high-throughput assays in subsequent fine-grained mechanistic experiments. Our scientific efforts are intimately linked to the clinic through a translational platform, which facilitates the longitudinal molecular monitoring of patients, thus providing mechanisms of evolution and adaptation to therapy.

Primary location: Cologne