VIJG LAB
Updated 440 days ago
1301 Morris Park Avenue, Room 450 Bronx, NY 10461
Life span is species-specific and determined by life history encoded by the species' total complement of genetic information. Our research has shown that the human life span has a natural limit that fluctuates around 115 years (Dong et al., 2016). This raises two questions. First, is it possible to break through that ceiling and develop interventions to increase the maximum human life span? Over the last two decades evidence with model organisms, from yeast and worms to flies and mice, has accumulated that life span can be significantly extended by targeting conserved pathways of aging...
Vijg Lab research interests, in general, is the process of human aging, its causal mechanisms and how these mechanisms limit the life span of our species. Dr. Jan Vijg was the first to develop transgenic mouse models for studying mutagenesis in vivo (in 1989)