HICKS

The stem cells of highly regenerative tissues associate with and are located in specialize compartments termed niches. Muscle stem cell niches are comprised of the myofiber sarcolemma and a laminin rich basal lamina containing dynamic ligand-receptor parts that support the stem cell. My work seeks to identify how emerging niches form and provide a new model for understanding human stem cell niche formation. Evaluating the regulators of emerging human niche formation during regeneration and development will improve our ability to generate de novo human niches and better support human muscle stem cells in vivo for cell therapy... We Utilize Emerging Technologies to Study and Improve Muscle Regeneration. We focus on the study of Muscle Stem Cell Biology.

Primary location: Irvine United States