ROYCHOUDHURI LAB

Our research aims to uncover the molecular and cellular mechanisms underpinning immune regulation and cancer immunosuppression... Immune regulation in inflammation and cancer. We are located at the Department of Pathology at the University of Cambridge, Cambridge, UK. We study the immunoregulatory mechanisms that suppress immune activation under homeostasis and cancer immunosuppression. We are interested in the differentiation and function of CD4+ T cells, including Foxp3+ regulatory T cells, and CD8+ T cells with cytotoxic function. We are interested in the mechanisms that restrict T cell activation and CD8+ T cell memory in the context of adoptive immunotherapy and immune checkpoint blockade therapy.

Primary location: Cambridge United Kingdom